Dear everybody,
I am writing to ask about micro challenge testing.
Could you help me with guidline for this
I appreciate your helps a lot
Posted 07 March 2017 - 06:55 AM
Dear everybody,
I am writing to ask about micro challenge testing.
Could you help me with guidline for this
I appreciate your helps a lot
Posted 08 March 2017 - 09:12 AM
Dear everybody,
I am writing to ask about micro challenge testing.
Could you help me with guidline for this
I appreciate your helps a lot
Hi akool,
This is a very wide subject.
Do you have any particular area of interest/application ?
Kind Regards,
Charles.C
Posted 09 March 2017 - 01:40 AM
Hi akool,
This is a very wide subject.
Do you have any particular area of interest/application ?
Dear Charles C,
Thank you for your precious response
My Japan customer ask for Microbio challenge testing activities in Lab. The framework include:
-Selection of pathogen or surrogate
-Level of challenge inoculum
-Duration of the study
-Formulation factors and processing condition
-Sample analyses and calculation of log reduction
-Interpretation of the data
-Pass / fail criteria & Recommendations
I wondering if there is any standard (ISO , AOAC, .....etc) for these activities and there is any guideline for these mentioned above
I wish you and everyone here who work with microbio challenge testing can help me
Sincerely yours.
Posted 09 March 2017 - 05:14 PM
Dear Charles C,
Thank you for your precious response
My Japan customer ask for Microbio challenge testing activities in Lab. The framework include:
-Selection of pathogen or surrogate
-Level of challenge inoculum
-Duration of the study
-Formulation factors and processing condition
-Sample analyses and calculation of log reduction
-Interpretation of the data
-Pass / fail criteria & Recommendations
I wondering if there is any standard (ISO , AOAC, .....etc) for these activities and there is any guideline for these mentioned above
I wish you and everyone here who work with microbio challenge testing can help me
Sincerely yours.
Hi akool,
Thks for details.
I am wondering why yr customer is asking for this info.
IMEX routine, in-plant labs infrequently perform such testing unless there is a specific necessity. Commercial analytical services do offer such facilities, eg
https://www.leatherh...llenge-testing/
http://www.merieuxnu...nge-studies/548
A detailed example of the theoretical/practical factors involved is attached -
challenge testing of micro,safety of raw milk cheeses,2011.pdf 1.92MB 21 downloads
and one more -
micro.challenge testing for L.monocytogenes,2014.pdf 579.49KB 25 downloads
Kind Regards,
Charles.C
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Posted 09 March 2017 - 05:43 PM
It depends. Is your process and product unique? If not, you will likely find the regulatory or peer-reviewed documentation to support the validation of your process and product.
For example, we produce milk in the US. Our validation for the milk processing/pasteurization is the FDA pasteurization time and temperature limits. All we do is reference that standard to validate.
Your process could be that simple.
Thanked by 1 Member:
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Posted 13 March 2017 - 08:48 AM
Hi akool,
Thks for details.
I am wondering why yr customer is asking for this info.
IMEX routine, in-plant labs infrequently perform such testing unless there is a specific necessity. Commercial analytical services do offer such facilities, eg
https://www.leatherh...llenge-testing/
http://www.merieuxnu...nge-studies/548
A detailed example of the theoretical/practical factors involved is attached -
challenge testing of micro,safety of raw milk cheeses,2011.pdf
and one more -
It depends. Is your process and product unique? If not, you will likely find the regulatory or peer-reviewed documentation to support the validation of your process and product.
For example, we produce milk in the US. Our validation for the milk processing/pasteurization is the FDA pasteurization time and temperature limits. All we do is reference that standard to validate.
Your process could be that simple.
Now i validate shelf life using durability .
So, are durability study and challenge testing independent?
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