VITAL® <
http://www.allergenb...net/vital/vital> is a standardised allergen risk assessment tool developed by the Australian Allergen Bureau to assist food producers to assess the impact of allergen cross contact and provide appropriate precautionary allergen labelling on their products. VITAL is not intended to be a replacement for mandatory labelling of allergens in food due to intentional inclusion as part of a recipe.
To assist food producers in implementing VITAL®, the Allergen Bureau has developed a spreadsheet based calculator which you can download free from the Allergen Bureau's website <
http://www.allergenb...vital-downloads>. The manufacturer enters information about the likely concentrations of cross contact allergens in a product arising from storage and handling of raw materials and from their specific manufacturing processes into the VITAL® calculator. Based on the estimated concentration of the allergen in typical serving (or Reference Amount) of the food it is assigned Action Level 1 or Action Level 2. Precautionary labelling is recommended for Action Level 2 foods.
The Reference Amount in the context of VITAL® is the maximum amount of a food eaten in a typical eating occasion. This may be the same as the Serving Size on the label or it may be appropriate to use the whole product as presented to the consumer. The Reference Amount is determined by the food producer/manufacturer based on their knowledge of the product.
The transition points or thresholds between the two action levels are based on Reference Doses, expressed in milligram total allergen protein, recommended by VITAL® Scientific Expert Panel (VSEP). The VSEP was established by the Allergen Bureau in collaboration with the Food Allergy Research & Resource Program (FARRP) at the University of Nebraska and at TNO in the Netherlands. The VSEP used dose-distribution modelling of individual oral clinical challenge data combined from a large number of sources and, based on the quality of data for each allergen, was able to recommend References Doses at which 99% or 95% of allergic individuals would be unlikely to react for most food allergens of concern. The work of the VSEP, including the References Doses has recently been published in detail Taylor et al 2014 <
http://www.sciencedi...278691513007072> and Allen et al 2013
<http://www.jacionline.org/article/S0091-6749(13)01059-2/abstract>.