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Posted 12 April 2016 - 08:59 AM

Hello all,


I want to conduct a cleaning validation to confirm that only acceptable limits of cleaning agent are present after cleaning. A final rinse test should be carried out. What is the acceptable limit of residual cleaning agent? And how is rinse volume included in my calculation?


Thanks for your help


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Posted 13 April 2016 - 12:44 PM

Hi Phia,




The acceptable level will be dependent on the cleaning chemical you are using, relevant legislation and your product.


Usually you would have a test method prescribed by your chemical supplier. Depending on the chemical, residues can be detected by test strips, titration, pH and taste.


Rinse volumes will depend on your cleaning chemical, it's concentration, how difficult it is to rinse (for example caustic is more difficult to rinse than acid) and the cleaning circuit. This is something that should be determined during the plant commissioning stage.


Kind regards,



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